03 // ANONYMIZED LONGITUDINAL BIOMARKER COHORT DOSSIERS
Quantified Shifts in ApoB, Fasting Insulin, VO2 Max & Methylation.
Explore four anonymized aggregate cohort protocols illustrating how serial 90-day diagnostics guide targeted clinical nutrition, training, and lipidology. Individual clinical outcomes vary.
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COHORT STUDY 01 // N=48 EXECUTIVES (AGES 42–58) · ILLUSTRATIVE AGGREGATE
ApoB & Non-HDL Atherogenic Particle Clearance Protocol
Lipidologist-Guided Therapy + Viscous Soluble Fiber + Zone-2
Despite 'normal' standard-panel LDL-C readings under 115 mg/dL, baseline NMR subfractionation revealed discordant ApoB particle counts above the 80th percentile. Individualized lipidologist protocols combined with soluble-fiber nutrition and hepatic insulin sensitization lowered median ApoB into the <65 mg/dL longevity target range. Individual clinical outcomes vary.
24-Week Quarterly Assay Follow-Up
Median ApoB 114 mg/dL → 62 mg/dL (-45.6%)
COHORT STUDY 02 // N=36 FOUNDERS (AGES 38–54) · ILLUSTRATIVE AGGREGATE
DEXA Visceral Adipose & Early HOMA-IR Reversal
CGM Glycemic Flattening + Hypertrophy Resistance + Sleep Architecture
Members presenting with normal HbA1c (5.3%) exhibited compensatory fasting hyperinsulinemia and elevated retroperitoneal visceral fat on baseline DEXA. Post-prandial CGM meal sequencing, progressive compound resistance training, and circadian sleep stabilization restored HOMA-IR below 1.2 while adding +1.9 kg appendicular lean mass. Individual clinical outcomes vary.
36-Week DEXA & CGM Intervention
Fasting Insulin 13.8 → 5.4 uIU/mL · VAT -38%
COHORT STUDY 03 // N=42 MEMBERS (AGES 45–64) · ILLUSTRATIVE AGGREGATE
Cardiopulmonary VO2 Max & Mitochondrial Lactate Shift
3x/Wk Lactate-Calibrated Zone 2 + 1x Norwegian 4x4 Peak Interval
Moving from the 40th age-decile aerobic percentile into the top 10% decile correlates with steep reductions in all-cause mortality hazard. Breath-by-breath metabolic cart testing pinpointed exact fat-oxidation heart-rate ceilings so busy executives trained 3.5 hours weekly without overtraining cortisol spikes. Individual clinical outcomes vary.
12-Month Biannual Metabolic Cart Tracking
Median VO2 Max 36.4 → 44.8 mL/kg/min (+23%)
COHORT STUDY 04 // N=31 ANNUAL MEMBERS · ILLUSTRATIVE AGGREGATE
DunedinPACE Epigenetic Aging Velocity Deceleration
hs-CRP Reduction + Methyl-Donor Sufficiency + Sleep Apnea Screening
Baseline DNA methylation arrays identified accelerated biological aging driven by subclinical periodontal/vascular inflammation (hs-CRP >1.8 mg/L), homocysteine elevation, and undiagnosed nocturnal hypoxia. Targeted root-cause remediation slowed measured epigenetic pace of aging by 0.22 years per calendar year. Individual clinical outcomes vary.
12-Month Multi-Modal Methylation Audit
Median DunedinPACE 1.06 → 0.84 yr/calendar yr
VERIDIAN CLINIC
Physician-led preventive longevity clinic uniting 112-biomarker blood panels, DunedinPACE epigenetics, radiation-free 3.0T MRI, and VO2 Max physiology. Informational pre-screening only — never submit PHI on public web forms.
DIAGNOSTIC SUITES
112-Biomarker & MRI Panels
Cohort Healthspan Outcomes
Annual Membership Tiers
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SAN FRANCISCO · NEW YORK · ZURICH · MAX 150 PATIENTS / MD